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10th International Influenza Meeting

Sep 13 – 15, 2026
University of Muenster (Castle)
Europe/Berlin timezone

Contact/Support: Orgalution GmbH

Session

Session 3: Viral Pathogenesis

Sep 14, 2026, 2:30 PM
Aula (1st floor)

Aula (1st floor)

Conveners

Session 3: Viral Pathogenesis

  • Oliver Planz

Presentation materials

There are no materials yet.

  1. 97. Emerging H5N5 clade 2.3.4.4b viruses with enhanced fitness in birds and mammals
    Ms Maryna Kuryshko (Friedrich-Löffler-Institut Bundesforschungsinstitut für Tiergesundheit)
    9/14/26, 2:30 PM
    Viral Pathogenesis
    Oral presentation

    H5N5 HPAIV clade 2.3.4.4b have increased in prevalence across Eurasia and North America and were associated with human infection in the US. Their evolution and zoonotic potential remain insufficiently characterised.
    We analysed global H5N5 prevalence (2000–2026) and assessed 4 representative viruses in chickens and ducks. Zoonotic potential was evaluated in airway epithelial (ALI) cultures...

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  2. 119. Microbiota dysbiosis in aging weakens gut–lung axis defense against influenza A virus
    Antje Häder
    9/14/26, 2:50 PM
    Viral Pathogenesis
    Oral presentation

    Aging alters the intestinal microbiota, reducing diversity, metabolic capacity, and antiviral defense along the gut–lung axis. This study investigated whether aging-associated microbial dysbiosis affects susceptibility to influenza A virus (IAV) and whether short-chain fatty acid (SCFA) supplementation can restore antiviral responses during cellular senescence.
    Using young and aged mice, we...

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  3. 156. Exploring the role of Klebsiella pneumoniae and bacteria-derived outer membrane vesicles (OMVs) in viral pneumonia using primary human lung models
    Dr Saskia Sophie Hinse (Department of Medicine V: Immunology of Respiratory Tract Infections Gießen)
    9/14/26, 3:10 PM
    Coinfections
    Oral presentation

    Bacterial co-infections are a common complication in respiratory viral infections. ICU patients with influenza and COVID-19 frequently develop co-infections with Gram-negative bacteria, particularly K. pneumoniae. Beyond direct bacterial infection, host lung tissue is exposed to extracellular outer membrane vesicles (OMVs), which modulate pulmonary immune responses. Using native distal lung...

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  4. 125. The Eye as a Gateway: Ocular Tropism, Host Responses and Transmission of Clade 2.3.4.4b H5 Viruses
    Dr Elsayed M. Abdelwhab (Friedrich-Loeffler-Institut)
    9/14/26, 3:30 PM
    Viral Pathogenesis
    Oral presentation

    Human infections with U.S. clade 2.3.4.4b H5N1 viruses frequently present with conjunctivitis, suggesting the eye as an important portal of infection. We compared the ocular tropism of U.S. H5N1 (B3.13 and D1.1) and European H5N1/H5N5 viruses in human conjunctival epithelial and corneal endothelial cells. All viruses infected human ocular cells, but the U.S. human H5N1 isolates displayed...

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  5. 94. The Respiratory Mucus Barrier: Friend or Foe in Zoonotic Influenza Transmission?
    Mr Maximilian Rohde (Helmholtz Center for Infection Research)
    9/14/26, 3:50 PM
    Viral Pathogenesis
    Oral presentation

    The ongoing spread of a highly pathogenic avian influenza virus (H5N1) in wild birds and poultry has increased global concern regarding the potential for zoonotic and pandemic spread of emerging influenza A viruses (IAV). Before viruses can infect epithelial cells, they must overcome the respiratory mucus barrier. Mucus in the airways can trap particles and promote their removal via...

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