Conveners
Session 5: Virus host cell interaction II
- Ursula Rescher
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Linda Brunotte9/15/26, 9:00 AMOral presentation
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Prerna Arora (Institute of Virology, University of Veterinary Medicine Hannover, Hannover, Germany)9/15/26, 9:30 AMVirus host cell interactionOral presentation
Influenza A viruses (IAVs) have recently expanded their host range to cattle, raising critical questions about tissue tropism, replication capacity, and consequences for dairy production and zoonotic risk. The detection of highly pathogenic avian influenza H5N1 in bovine milk highlights the mammary gland as a previously underappreciated site of infection and viral shedding.
To study...
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Jamina Molsen (Institute of Virology, Medical Center University of Freiburg, Freiburg, Germany)9/15/26, 9:50 AMVirus host cell interactionOral presentation
Zoonotic infections with influenza A viruses (IAVs) of animal-origin are typically self-limiting but can occasionally give rise to pandemics provided human host barriers are overcome. The recently identified human BTN3A3 (butyrophilin subfamily 3 member A3) is a potent restriction factor for zoonotic IAVs. Human-adapted IAVs overcome BTN3A3 restriction through adaptive residues 52 (N, H, Q) or...
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Dr Steinar Mannsverk (Uppsala University)9/15/26, 10:10 AMVirus host cell interactionOral presentation
Influenza A virus (IAV) initiates infection by binding sialylated glycans on the host cell surface, yet the membrane factors regulating this interaction remain incompletely understood. Here, we investigated how the host membrane lipid composition regulates IAV attachment and fusion using single-virus microscopy in chemically defined membrane systems, complemented by biophysical measurements....
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