Conveners
Session 6: Antivirals & vaccines
- Yvonne Börgeling
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Andres Pizzorno9/15/26, 11:00 AMOral presentation
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Amina Qadir (University of Oxford)9/15/26, 11:30 AMAntivirals and VaccinesOral presentation
The influenza A virus nucleoprotein (NP) is an essential and highly conserved component of the viral ribonucleoprotein (vRNP) complex, where it mediates viral RNA encapsidation and coordinates multiple steps of the viral replication cycle. Despite its essential role, NP remains unexplored as a therapeutic target.
To identify chemical starting points for structure-based inhibitor design, we...
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Sarah Heynen (University of Veterinary Medicine Hannover, Clinic for Poultry)9/15/26, 11:50 AMAntivirals and VaccinesOral presentation
Zoonotic highly pathogenic avian influenza viruses (HPAIV) are endemic in Europe and a threat to poultry but also mammalian health. Control strategies relied on culling of infected birds. The Delegated Regulation (EU) 2023/361 enables now the European Union member states to decide for vaccination. However, the impact of a vaccination campaign depends on the successful implementation at farm...
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110. Improving Immune Responses In Avian IAV H5 Immunization By Sustained Antigen Release TechnologySophie Winter (University of Turku)9/15/26, 12:10 PMAntivirals and VaccinesOral presentation
Recent global outbreaks of highly pathogenic avian influenza A(H5N1) highlight the need for vaccines that can prevent human transmission. Seqirus’s zoonotic influenza A(H5N8) vaccine (approved in 2024) protects against clade 2.3.4.4b H5N1 viruses but requires a booster, which may reduce compliance. Prolonged antigen exposure can strengthen humoral immunity; therefore, sustained antigen release...
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