9–11 Oct 2023
Mercure Hotel MOA Berlin
Europe/Berlin timezone

Joint analysis of antimicrobial resistance data from human and veterinary sector - results from the project Connect One Health Data

10 Oct 2023, 14:00
15m
MOA 6

MOA 6

Oral presentation Antimicrobial Use & Resistance Session 8: Antimicrobial Use and Resistence

Speaker

Katja Hille (Department for Infectious Disease Epidemiology, Public Health Agency of Lower Saxony)

Description

In the Connect One Health Data project, routine data on resistance testing in Lower Saxony from the zoonoses monitoring (ZooMo; veterinary sector) are analysed together with data from the antibiotic resistance monitoring in Lower Saxony (ARMIN; human sector) for the years 2018-2021. Proportions of resistant isolates per antimicrobial agent in the different populations are determined.
The following germ were included in the analyses: E. coli, Enterococcus faecalis, Enterococcus faecium, and MRSA. For each germ, antimicrobials for which test results were available from both sectors were included for joined analyses.
For MRSA as an example, 15 antimicrobials could be included in the analysis. In ZooMo, 217 MRSA isolates were tested for all antimicrobials, compared to 98 - 14,460 tested isolates in the ARMIN data, where the number of tests varied by antimicrobial agent. About 20% of human MRSA isolates (n = 13,077) are resistant to tetracycline, in contrast to about 90% of tetracycline resistant broiler isolates (n=15).
When interpreting the data, the background of sampling must be taken into account: fixed sampling design of healthy animals along the food chain (ZooMo) vs. passive surveillance of human patients (ARMIN). In addition, laboratory methods and interpretation standards differ between the sectors. Therefore, we are currently analysing the impact of the use of the different standards on the proportions of resistance.

Keywords

surveillance, interpretation standards, MRSA, E. coli, Enterococcus

Junior Scientist Status No, I am not a Junior Scientist.
Registration-ID code ZOO23-455
Professional Status of the Speaker Senior Scientist

Primary authors

Katja Hille (Department for Infectious Disease Epidemiology, Public Health Agency of Lower Saxony) Katja Nordhoff (Lower Saxony State Office for Consumer Protection and Food Safety) Alexandra Irrgang (Department Biological Safety, Unit Epidemiology, Zoonosis and Antimicrobial Resistance, German Federal Institute for Risk Assessment) Anne Schnepf (Department of Biometry, Epidemiology and Information Processing, WHO-CC for Research and Training for Health at the Human-Animal-Environment Interface, University of Veterinary Medicine Hannover) Karen Remm (Lower Saxony State Office for Consumer Protection and Food Safety) Katrin Kunze (Lower Saxony State Office for Consumer Protection and Food Safety) Martina Scharlach (Department for Infectious Disease Epidemiology, Public Health Agency of Lower Saxony) Reinhard Velleuer (Lower Saxony State Office for Consumer Protection and Food Safety) Eberhard Haunhorst (Lower Saxony State Office for Consumer Protection and Food Safety) Johannes Dreesman (Department for Infectious Disease Epidemiology, Public Health Agency of Lower Saxony) Lothar Kreienbrock (Department of Biometry, Epidemiology and Information Processing, WHO-CC for Research and Training for Health at the Human-Animal-Environment Interface, University of Veterinary Medicine Hannover)

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