Calvin Mehl
(Friedrich-Loeffler-Institut (FLI), Federal Research Institute for Animal Health, Greifswald-Insel Riems, Germany. German Centre for Infection Research (DZIF), Partner Site Hamburg-Lübeck-Borstel- Riems, Germany.)
Rodents are the most speciose mammalian group, encompassing some ~2300 species. This great diversity is associated with a correspondingly significant pathogen diversity, including Seoul virus, lymphocytic choriomeningitis virus (LCMV), rat hepatitis E virus, Leptospira spp. and Streptobacillus moniliformis. Commensal rodent species such as Norway rats (Rattus norvegicus) and house mice (Mus musculus) are particularly important pathogen reservoirs because of their close association with humans. Here, we present the results from several rodent pathogen studies from Europe and the Middle East. We describe the prevalence and diversity of rodent-borne pathogens in urban areas, and present case studies from zoos in Germany. In Iran we detected the presence of eight different pathogens, several of which being zoonotic, and multiple coinfections. We were also able to detect several mutations of the Vkorc1 gene in these rats, which is responsible for resistance to anticoagulant rodenticides. In German zoos we describe the potential spill-over of Francisella tularensis and LCMV from wild rodents to captive monkeys. Furthermore, we describe the re-emergence and persistence of LCMV in a mouse population in Germany and the potential for spill-over events in zoos. These studies highlight the need for continued pest rodent management and surveillance, and the potential risk these animals pose for the emergence and re-emergence of zoonotic pathogens.
Keywords
rodents, ecology, LCMV, rat hepatitis E virus, Germany, zoos
Professional Status of the Speaker |
PhD Student
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Junior Scientist Status |
Yes, I am a Junior Scientist.
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Registration-ID code |
ZOO23-599
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Calvin Mehl
(Friedrich-Loeffler-Institut (FLI), Federal Research Institute for Animal Health, Greifswald-Insel Riems, Germany. German Centre for Infection Research (DZIF), Partner Site Hamburg-Lübeck-Borstel- Riems, Germany.)
Allison Groseth
(Friedrich-Loeffler-Institut (FLI), Federal Research Institute for Animal Health, Greifswald-Insel Riems, Germany. )
Olayide Abraham Adeyemi
(Friedrich-Loeffler-Institut (FLI), Federal Research Institute for Animal Health, Greifswald-Insel Riems. )
Tobias Eisenberg
(Hessian State Laboratory, 35392 Giessen, Germany. Institute of Hygiene and Infectious Diseases of Animals, Justus-Liebig-University Giessen, 35392 Giessen, Germany. )
Alma Gedvilaitė
(Institute of Biotechnology, Life Sciences Center, Vilnius University, Saulėtekio al. 7, LT-10257 Vilnius, Lithuania.)
Gerald Heckel
(University of Bern, Institute of Ecology and Evolution, Bern, Switzerland. )
Dirk Höper
(Friedrich-Loeffler-Institut (FLI), Federal Research Institute for Animal Health, Greifswald-Insel Riems, Germany. )
Gabriele Ismer
(Tierpark Gettorf GmbH, Gettorf, Germany.)
Jörg Linde
(Friedrich-Loeffler-Institut (FLI), Federal Research Institute for Animal Health, Institute for Bacterial Infections and Zoonoses (IBIZ), Jena, Germany. )
Anna Obiegala
(University of Leipzig, Institute of Animal Hygiene and Veterinary Public Health, 04103 Leipzig, Germany.)
Mohammad Reza Abai
(Tehran University of Medical Sciences, School of Public Health, Department of Medical Entomology and Vector Control, Tehran, Iran.)
Gereon Schares
(Friedrich-Loeffler-Institut (FLI), Federal Research Institute for Animal Health, Greifswald-Insel Riems, Germany. )
Herbert Tomaso
(Friedrich-Loeffler-Institut (FLI), Federal Research Institute for Animal Health, Institute for Bacterial Infections and Zoonoses (IBIZ), Jena, Germany.)
Rainer G. Ulrich
(Friedrich-Loeffler-Institut (FLI), Federal Research Institute for Animal Health, Greifswald-Insel Riems, Germany. German Centre for Infection Research (DZIF), Partner Site Hamburg-Lübeck-Borstel- Riems, Germany.)
Emilija Vasiliūnaitė
(Institute of Biotechnology, Life Sciences Center, Vilnius University, Saulėtekio al. 7, LT-10257 Vilnius, Lithuania.)
Claudia Wylezich
(Friedrich-Loeffler-Institut (FLI), Federal Research Institute for Animal Health, Greifswald-Insel Riems, and Justus-Liebig-Universität Gießen, Institut für Angewandte Mikrobiologie, Gießen, Germany. )
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