ISIDORe is a new approach to epidemic preparedness and response research in Europe. It assembles and provides free access to an unprecedented One Health-driven integrated portfolio of cutting-edge research resources, dedicated to the study of any epidemic-prone disease, including viral zoonoses. ISIDORe involves all the major European Research Infrastructures and networks in the field of...
Mosquito-borne diseases are responsible for a yearly spillover to around 700 million people. Early warning surveillance tools are needed to prevent disease spread to humans and animals in times of climate change and globalization. The aim of this study was to develop a field deployable sequencing platform to identify potential mosquito pathogens, species and host from blood meals. A rapid...
Strong One Health (OH) research platforms are a cornerstone of pandemic preparedness. While many pathogens underlying acute febrile illnesses (AFI) are zoonotic, animal and OH research targeting AFI is limited and the underlying infectious agents often remain underdiagnosed. In 2022, we started the implementation of an interdisciplinary study to characterize AFI in Guinea, the Fever Project. A...
Tick-borne encephalitis (TBE) is the most important tick-borne viral disease in Central Europe. Since the introduction of an effective vaccine no seroprevalence studies have been possible. Therefore, no actual data on the incidence and prevalence of TBE infection in a population is currently available.
We developed an ELISA to detect IgG antibodies against NS1 antigen of TBEV indicating...
Spreading of antibiotic resistance is one important threat for human health. Microorganisms with resistance deteriorate the effectiveness of antibiotics, which are the first choice in controlling and treating infectious diseases. There are three main ways to transfer antimicrobial resistance. Due to high selection pressure, antibiotic resistance more often develop and spread in hospitals, is...
Since no vaccination against Lyme borreliosis (LB) is available, individual protective measures are prevention options. However, application depends on knowledge and perceptions. We asked LB cases about their knowledge, attitudes and behavior (KAB) regarding tick prevention and tick-borne diseases to inform future prevention campaigns.
We invited a subset of LB cases reported between weeks...
