10–12 Sept 2025
Kaiserin-Friedrich-Stiftung, Berlin
Europe/Berlin timezone

Feline Bocaparvovirus in domestic cats with gastrointestinal disease

11 Sept 2025, 16:15
15m
Seminar Room

Seminar Room

Oral presentation Veterinary Bacteriology, Mycology and Virology Viral Pathogenicity I

Speaker

Dr Anna Salvaggiulo (Department of Veterinary Medicine, University of Bari, Valenzano (Bari), Italy)

Description

Bocaparvoviruses (BoVs) are non-enveloped viruses with linear single-stranded DNA genome and are classified in the genus Bocaparvovirus (subfamily Parvovirinae, family Parvoviridae). BoVs infect the respiratory and gastrointestinal tracts of young animals and humans and have been detected in a wide range of mammalian hosts (i.e. primates, carnivores, ungulates and rodents). In cats, feline BoV (FBoV) has been identified in three genetic types, namely FBoV-1, -2, and -3 (Bocaparvovirus carnivoran 3, 4 and 5, respectively), which have been described in cats with gastrointestinal symptoms. We investigated the prevalence of FBoV in 126 feline rectal swab samples of cats with gastroenteritis from two different regions, Apulia (collection A, 101 samples) and Abruzzi and Molise (collection C, 25 samples) between 2023 and 2025. We used a pan-bocavirus PCR assay with broadly reactive primers able to identify all human and animal BoVs. Overall, 16.7% (21/126) stool samples tested positive for BoVs. Partial NS1 sequences were generated for 9 strains, with nucleotide identities ranging from 95.0 to 100% to FBoV-1 strains. A quantitative PCR assay specific for FBoV-1 was designed and used to re-screen the sample collections, with an infection rate of 19.0% (24/126). Gathering epidemiological data is necessary to improve our understanding of the enteric virome of companion animals.

Keywords

feline, Bocaparvovirus, gastrointestinal disease, virus discovery

Registration ID ECVM25-86
Professional Status of the submitter, who is also the speaker PhD Student

Author

Dr Anna Salvaggiulo (Department of Veterinary Medicine, University of Bari, Valenzano (Bari), Italy)

Co-authors

Dr Francesco Pellegrini (Department of Veterinary Medicine, University of Bari, Valenzano (Bari), Italy) Prof. Michele Camero (Department of Veterinary Medicine, University of Bari, Valenzano (Bari), Italy) Dr Gardenia Gatta (Istituto Zooprofilattico Sperimentale dell'Abruzzo e del Molise, Teramo, Italy) Dr Nicandro Rodi (Istituto Zooprofilattico Sperimentale dell'Abruzzo e del Molise, Teramo, Italy) Dr Alessio Lorusso (Istituto Zooprofilattico Sperimentale dell'Abruzzo e del Molise, Teramo, Italy) Prof. Gabriella Elia (Department of Veterinary Medicine, University of Bari, Valenzano (Bari), Italy) Prof. Nicola Decaro (Department of Veterinary Medicine, University of Bari, Valenzano (Bari), Italy) Prof. Vito Martella (Department of Veterinary Medicine, University of Bari, Valenzano (Bari), Italy) Prof. Gianvito Lanave (Department of Veterinary Medicine, University of Bari, Valenzano (Bari), Italy)

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