Speaker
Description
Methicillin-resistant Staphylococcus pseudintermedius (MRSP) and Staphylococcus aureus (MRSA) are important pathogens in companion animals with implications for both animal and human health due to their zoonotic potential. This retrospective study evaluated MRSP and MRSA presence in samples from animals with various clinical conditions. Bacterial identification was performed by MALDI-TOF, and antimicrobial resistance was assessed via MICs and PCR targeting the mecA gene. Clinical conditions were classified using anamnestic data, cytology, or histopathology. Methicillin resistance was detected in 48/128 (37%) S. pseudintermedius and 2/9 (22%) S. aureus, corresponding to 50/137 (36%) of the total isolates. Particularly, MRS was found in 26/69 (38%) of suspected urinary infections, 8/34 (23%) otitis externa, 8/18 (44%) pyodermitis, and 8/16 (50%) surgical site infections. No statistical association was found between clinical condition and MRS presence. The highest resistance rates were against penicillin (84%), erythromycin (55%), clindamycin (46%), enrofloxacin (37%), marbofloxacin (37%), doxycycline (37%), pradofloxacin (36%), oxacillin (36%), trimethoprim/sulfamethoxazole (34%), chloramphenicol (31%), gentamicin (25%), and 1% for amikacin, nitrofurantoin, and florfenicol. Our findings indicate a high prevalence of MRS across clinical conditions, suggesting that methicillin resistance should always be suspected in clinical practice.
Keywords
Methicillin-resistance, Staphylococcus aureus, Staphylococcus pseudintermedius, Companion animals
| Registration ID | ECVM25-128 |
|---|---|
| Professional Status of the submitter, who is also the speaker | Senior Scientist |
Author
Co-authors
External references
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