7th International Conference of the European College of Veterinary Microbiology (ECVM)

Session

AMR & Evolution - ES

11 Sept 2025, 14:45

Lecture Hall

Conveners

AMR & Evolution - ES

• Flavia Zendri (University of Liverpool)
• Raffaele Scarpellini (University of Bolgona)

151. Chromosomal ampR Regulates Plasmid-Mediated Antibiotic Resistance and Gene Duplication Amplification in Enterobacter cloacae

Yuwen Fang (Institute of Microbiology and Epizootics, Centre for Infection Medicine, School of Veterinary Medicine, Freie Universität Berlin, Berlin, Germany)

11/09/2025, 14:45

Antimictobial Resistance

Oral presentation

Background and Objectives: Gene duplication and amplification (GDA) is crucial for bacterial adaptation to antibiotic pressure [1]. In Enterobacter cloacae strain IMT49658-1, ceftazidime induces GDA of a genomic region containing blaDHA and adjacent ampR(DHA) [2]. The strain also carries plasmid-borne blaTEM and blaCTX, and chromosomal blaACT with ampR(ACT). Given the regulatory role of...

20. Within-host evolution of Staphylococcus pseudintermedius in dogs with skin disease

Kate Worthing (The University of Sydney)

11/09/2025, 15:00

Antimictobial Resistance

Oral presentation

This study assessed within-host phenotypic and genotypic evolution amongst methicillin-resistant Staphylococcus pseudintermedius (MRSP) isolates from two dogs with chronic skin disease and recurrent pyoderma. Phenotypic antimicrobial susceptibility was determined by broth microdilution. Isolates underwent genome sequencing using both short read and long read platforms. Genome short reads were...

150. Investigating the Role of the DUF445-Containing Putative Membrane Protein in Albicidin Resistance in Acinetobacter baumannii IMT51508

Sana Khan (Institute of Microbiology and Epizootics, Freie Universität Berlin, Berlin, Germany)

11/09/2025, 15:15

Genomics

Oral presentation

Albicidin, a promising antibacterial peptide, functions by inhibiting the activity of bacterial DNA gyrase. This study aims to elucidate the mechanisms underlying albicidin resistance in ESKAPE pathogens, which are leading contributors to nosocomial infections. Specifically, we focus on investigating the resistance mechanisms in Acinetobacter baumannii (IMT51508), a clinically significant...