Conveners
Omics techniques
- Jasmin Wenderlein (Bundesinstitut für Risikobewertung)
- Istvan Szabo (Bundesinstitut für Risikobewertung)
This study aims to deepen the mapping of bacteria that may participate in infectious processes as pathobionts, using information obtained from short-read sequencing and the subsequent assembly of genomes from these reads, a method known as metagenome-assembled genomes (MAGs) in an experimental infection model of swine dysentery by Brachyspira hyodysenteriae. Shotgun metagenomic sequencing with...
Dissecting intestinal homeostasis requires understanding subtle interactions between host genetics, innate immunity, and the microbiota before overt disease occurs. Using genetically diverse pigs, we mapped O-glycan structures in intestinal mucus under non-induced conditions, integrating these with transcriptomic and microbiota data. Porous graphitized carbon LC-MS/MS identified ~140 distinct...
Aeromonas salmonicida subsp. salmonicida is the etiological agent of furunculosis, a fish disease highly aggressive for salmonids and responsible for significant economic losses in aquaculture worldwide. This study aimed to explore genomic and antimicrobial resistance traits of Western European A. salmonicida subsp. salmonicida strains and to develop an adapted Galleria mellonella infection...
Objectives: The mechanisms regulating the interconnections between viruses and cell hosts are not yet fully understood and this is necessary for early diagnosis and an effective operational response to counter infections caused by emerging and/or re-emerging viruses. Metabolomics gives a comprehensive representation of metabolites providing further information on mechanisms involved in cell...
Vibrio parahaemolyticus is a major food-borne pathogen associated with contaminated seafood and capable of causing varying degrees of gastroenteritis in humans. Its pathogenicity is mediated by multiple virulence factors, including flagella and adhesion factors, and is further enhanced by its ability to form biofilms, increasing its resistance to environmental stress. However, the mechanisms...
