Conveners
Session 11: Vaccines & Immunology
- Corinna Pietsch
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Jonas Schmidt-Chanasit10/7/26, 9:45 AMVaccines & ImmunologyOral presentation
Chikungunya virus (CHIKV) is re-emerging as a One Health threat at the human-vector-climate interface. WHO and ECDC data show major resurgence in 2025-2026, with large outbreaks in the Indian Ocean and the Americas and substantial autochthonous transmission in Europe, including 788 confirmed locally acquired cases in France and 384 in Italy in 2025. European evidence, indicates that once...
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Prof. Julia R. Port (Laboratory of Transmission Immunology, Helmholtz Center for Infection Research, Braunschweig, Germany)10/7/26, 10:00 AMVaccines & ImmunologyOral presentation
MPXV comparative biology after mucosal exposure remains unclear. We compared clades Ia (Zaire and Republic of Congo isolates), IIa, and IIb in a cynomolgus macaque respiratory infection model to assess disease, viral shedding, and immune responses. Mucosal infection caused milder, more localized disease than high-dose aerosol or intravenous models. Clade Ia (Zaire) and IIa produced stronger...
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Ms Jailene Castillo10/7/26, 10:15 AMVaccines & ImmunologyOral presentation
The remarkable zoonotic competence of Influenza A virus (IAV) warrants dedicated One Health vigilance. As the cause of four disruptive pandemics in the last century, pervasiveness into previously unaffected regions, and elevated incidence of human and animal infections, IAV continues to circulate across multiple host species. Most of the research on IAV entry has investigated interactions...
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Ms Marie Demuth (Centre for Biological Threats and Special Pathogens (ZBS), Robert Koch-Institute, Berlin, Germany), Dr Daniel Bourquain (Centre for Biological Threats and Special Pathogens (ZBS), Robert Koch-Institute, Berlin, Germany)10/7/26, 10:30 AMVaccines & ImmunologyOral presentation
Hantaviruses maintain persistent and asymptomatic infections in their mammalian reservoir hosts but can cause severe disease when transmitted to humans. In Europe, Puumala virus (PUUV) is the most important cause of human hantavirus infections. To investigate if hantavirus disease in humans is driven by an overreactive immune response, we aimed to compare PUUV replication and innate immune...
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